We have developed a range of software tools within the MRC Integrative Epidemiology Unit. This includes:

  • MR-Base is a comprehensive database of GWAS summary statistics and an analytical platform for two-sample Mendelian randomization
  • LD Hub is a database of GWAS summary statistics and an analytical platform for LD score regression
  • MELODI is a literature mining platform to identify potential mechanistic pathways between an exposure and outcome
  • FATHMM is a suite of genetic variant effect prediction algorithms

We also have a range of old software tools developed by the group.

LD Hub – LD score regression
MELODI – literature mining
FATHMM – variant effect prediction
MR-Base – 2-sample Mendelian randomization